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What is the Nexium 24HR Challenge?

Take one Nexium 24HR tablet each day, and you can get 24 hour protection for lasting frequent heartburn relief1. Nexium 24HR can help treat the heartburn which prevented you from getting a good nights’ sleep and eating some of the food you love during the day, so that you can feel like yourself again.

What to expect from the challenge?

Day 1

Nexium Challenge

Add Nexium 24HR to your routine and take one tablet at about the same time each day. Keeping a regular time, e.g. in the morning, will help to remind you to take it. It begins working within hours and some people may feel the benefits that day, or by the evening1. You may need to take Nexium 24HR for a few days before experiencing the full effect.

Day 2-6

Nexium Challenge

Each day you could be experiencing further improvements and feel a difference in your heartburn symptoms1. Improvements may include a reduction in heartburn related sleep disturbances1,2.

Day 7-14

Nexium Challenge

Controlling your heartburn can improve sleep quality, productivity and daily functioning3.

Nexium Challenge


Tell your doctor or pharmacist if you do not feel better while taking Nexium 24HR. If symptoms persist or recur within 2 weeks of completing the course, consult your doctor. Further examination may be required.


1. Peura DA et al. BMC Gastroenterol. 2018;18:69.
2. Johnson DA, et al. CMRO 2015;31(2): 243-250.
3. Kulig M et al. Aliment Pharmacol Ther. 2003;18:767-76.